WISSPAR

A curated immunogenicity database

The Worldwide Index of Serotype Specific Pneumococcal Antibody Responses (WISSPAR) is a centralized platform housing data on immunogenicity from clinical trials of pneumococcal vaccines.  The data on WISSPAR are primarily curated from outcomes tables from clinicaltrials.gov and are made available in a searchable format that can be readily used for downstream analyses. Fields included in the database include product, manufacturers, dosing schedule, age group, and geographic region. You can use the embedded tools to generate customizable visualizations, export data for further analyses, or just browse through clinical trial results.

Please note that immunogenicity data should be compared and interpreted with caution. Data on immunogenicity alone cannot be used to infer differences in effectiveness between vaccines. These data need to be combined with information on the protective concentration of antibodies required to protect against each serotype in different populations for meaningful comparisons.

WISSPAR is a collaborative effort between the Yale School of Public Health and the Johns Hopkins Bloomberg School of Public Health. The development of this tool was supported by the Bill and Melinda Gates Foundation. For issues or suggestions, please email [email protected]. There is also the possibility of creating custom, private data access portals for specific use case; please email for details.